Mark R. Cobain a, John P. Foreyt b, a Unilever Corporate Research, Colworth House, Sharnbrook, Bedfordshire MK46 4AA, UK Abstract The central hypothesis examined in this issue is that insulin resistance promotes maladaptive brain function and contributes to reduced neuronal plasticity, potentially accelerating brain aging. Therefore, if we were to prevent or treat insulin resistance, …
Robert E. Burke. Laboratory of Neural Control, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20895, USA. Abstract This chapter deals with the central role that Sir John Eccles played in the elucidation of the mechanisms of synaptic transmission within the central nervous system during the three decades between the …